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Serum neurofilament light: a biomarker of neuronal damage in multiple sclerosis

Imagine you need to get a vital message to a castle surrounded by a moat and high walls (your cell)

Both free iron and labile iron, including non-transferrin-bound iron, catalyze the formation of ROS via the Fenton and HaberWeiss reactions, which can impact hepatic mitochondrial, microsomal, and lysosomal function [80,81,82]

Therefore, the current study analysed the relationship between these markers and determined whether serum AGEs, RAGE, sRAGE, IGF-1, and IGF-1R function as influencing variables for the risk of developing CRC in patients with T2DM